LH is the pituitary signal that tells your body to produce testosterone or estrogen. Low pulsatility is a common root cause of low-T symptoms despite "normal" total testosterone—because the signal to produce more never fires strongly enough.

SHBG binds sex hormones and takes them out of circulation. High levels can mask what's really low bioavailable testosterone or estrogen, even when total levels look fine. This is the "hidden half" that standard hormone panels ignore.

Aromatase enzyme activity determines how much testosterone converts to estrogen. High converters—often signaled by weight around the middle—benefit from natural aromatase inhibitors like zinc, DIM, and weight training. Low converters rarely need to think about it.

Your individual optimal TSH is often narrower than the lab reference range. Someone who feels best at 1.0 will feel terrible at 3.5—even though both are "normal." Knowing your sweet spot ends years of being told "you're fine" when you're clearly not.